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LX-1031 br Results and discussion br Conclusions
2021-04-19

Results and discussion Conclusions In this work, we have conjugated two thermophilic enzymes (i.e., AMY and LASPO) to iron oxide NPs through different conjugation strategies obtaining efficient biocatalysts. We have demonstrated that these NP-enzyme systems can be successfully activated by an
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Materials and methods br Results Assay of botulinum toxin
2021-04-19

Materials and methods Results Assay of botulinum toxin activity is critical for the risk-assessment, diagnosis, and treatment of botulism cases. The frequently encountered active forms of the toxin are; L chain (inside intoxicated neuronal cells), BoNT (in the blood stream of a botulism patient,
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br Results br Discussion The process by which
2021-04-19

Results Discussion The process by which MBCs differentiate from GC B cell precursors remains mostly uncharacterized, in large part because of the uncertainty surrounding the nature of the precursor Pentamidine dihydrochloride within the GC. The identification here of a distinct subset of GC B
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Environmental cues such as microbial dietary
2021-04-19

Environmental cues, such as microbial, dietary, and neuronal signals, regulate the differentiation and function of ILC3s. However, the identities of any additional cues and the receptors that detect them remain unknown. An important class of proteins enabling cells to sense extracellular cues are G-
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E protein was studied using
2021-04-19

E1 protein was studied using specific anti-E1 SJB2-043 sale in wild type cells and in transfected cells overexpressing the enzyme. The results revealed several unusual characteristics, which are unique to this ubiquitin-activating enzyme. The E1 was translated as a full-length protein and then quic
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br Materials and methods br Results br
2021-04-19

Materials and methods Results Discussion The present study shows that 1) overexpression of wild-type or mutant α-SYN interferes with forskolin-induced DBH up-regulation, 2) α-SYN enters into the nucleus and is able to bind to CRE region, compete for CREB, and attenuate CRE-mediated transcri
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GFP Quantitation Kit The data from the Sur lab have showed
2021-04-19

The data from the Sur lab have showed DNA-PK is involved in metabolic gene regulation in response to insulin. DNA-PK regulates fatty GFP Quantitation Kit synthesis by modulating the protein expression of fatty acid synthase (FAS) in a feeding-dependent manner. DNA-PK induces the activation of Upstre
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Long stretches of ssDNA have also been observed in rad
2021-04-19

Long stretches of ssDNA have also been observed in rad53-1 mutant Epibrassinolide synthesis under replication stress using EM images (Sogo et al., 2002). Deletion of EXO1, a 5′-to-3′ exonuclease, can suppress the generation of ssDNA detected in rad53-1 mutant cells (Cotta-Ramusino et al., 2005). It
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If the unwanted objects detected by OpenComet are manually d
2021-04-19

If the unwanted objects detected by OpenComet are manually deleted, and then the DNA (%) in tail is computed, the performance of the present method can be compared more effectively. Therefore, performance of OpenComet is analysed in two ways as Approach 1 and Approach 2. Approach 1, considers the DN
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br Conflicts of interest br Introduction Diacylglycerols
2021-04-19

Conflicts of interest Introduction Diacylglycerols (DAGs) and phosphatidic Oxybutynin (PA) play fundamental roles in biology as basic components of membranes, intermediates in lipid metabolism, and secondary messengers in cellular signaling (Carrasco and Merida, 2007, Fang et al., 2001). Cell
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br Results and discussion To
2021-04-19

Results and discussion To check the Deferasirox that the charge of α-synuclein can be altered due to the glycation, we measured zeta potential of native α-synuclein and α-synuclein glycated by two different glycating agents, methylglyoxal (MG) and glyceraldehyde-3-phosphate (GA-3-P). The value f
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DDR is characterized by an N terminal discoidin domain
2021-04-19

DDR2 is characterized by an N-terminal discoidin domain and a C-terminal kinase domain [7]. Characteristics of DDR1, which is a homologue of DDR2, have been extensively investigated in terms of expression level in cancer tissues and biological functions in normal and cancer cell conditions, but char
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br Conclusion In this work experiments were carried
2021-04-17

Conclusion In this work, experiments were carried out to purify the protein with COX activity, using an anti-mouse COX-2 pAb and a COX activity assay as tools for monitoring the protein responsible for this activity in the parasite. Gp63 enrichment through the affinity column and identification b
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Like all other cellular processes ubiquitination is also tig
2021-04-17

Like all other cellular processes, ubiquitination is also tightly regulated; more so, as myriads of pathways are controlled via this conjugation and dysregulation of ubiquitination has been implicated in various diseases including cancer [16], [17]. Quite a few of such regulatory mechanisms that con
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The BMP family comprises significant growth factors for
2021-04-17

The BMP family comprises significant growth factors for the regeneration of bone and cartilage. Among these, BMP- has been known as an early marker during the proliferation of osteoblast cells, and one of the most potent stimulators of osteoblastic cells differentiation [40]. Studies with COX-2 knoc
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